2026 NewYorkCISO ORBIE Awards

2026 NewYorkCISO ORBIE Awards · Super Global Finalist

Sydney Klein

SVP, CISO & Head of Enterprise IT

Bristol Myers Squibb

Sydney Klein

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Bio

Sydney Klein is Global Chief Information Security Officer and Head of Enterprise IT at Bristol Myers Squibb (BMS) where she leads cybersecurity, infrastructure, data, AI deployment, and digital workforce experience, balancing innovation and security to create trust among key stakeholders. Previously, Sydney spent nearly 20 years as VP, Cyber at Capital One. A sought-after thought leader and speaker, she has received numerous honors including Top 10 CISO (2022-2023), and Top 100 Women in Cyber (2024).

Success Story

As a key leader in BMS, Sydney has transformed the company’s approach to secure digital innovation. Under her leadership, cybersecurity has evolved from a reactive function to a strategic enabler of resilience and trust. Sydney has steered BMS’s Cyber Fusion Center to become a proactive, intelligence-driven command hub, integrating threat detection, incident response, and vulnerability management capabilities. This transformation enables incident response in minutes rather than hours, minimizing business impact. Her team’s deployment of best in class security tools enhance detection of sophisticated phishing attempts, while the introduction of streamlined authentication tools has strengthened BMS’s cybersecurity without compromising user experience.

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